Will Pope Francis Be an Agent of Change?

Pope Francis helped renew diplomatic relations between the US and Cuba. Now he's visiting both countries, with a lot to say about their different ideologies, economies and treatment of those Jesus called "the least among us."

Also, why defection stories could battle ISIS propaganda. On today's Talking Point, the best-known drug for a rare disease has been sold for $13.50. Suddenly it costs $750. Can the health system sustain that and other gigantic increases?

Pope Francis climbs the steps to the altar upon arriving to give the first mass of his visit to Cuba in Havana's Revolution Square, September 20, 2015. Across from the square is a portrait of Che Guevara on the front of the Interior Ministry building. (Tony Gentile/Reuters)