Violence has erupted again in Egypt, where supporters of former President Mohammed Morsi are demonstrating against the government that ousted him in July. The government has designated the Muslim Brotherhood, which backed Egypt's first democratically elected leader, a terrorist organization and is responding to dissent, which comes ahead of an upcoming constitutional referendum, with increasing force and arrests. Will this further radicalize Islamists in Egypt? Will the violence spill over into the rest of the region? What role should the United States play in a Middle East marked by the rise of al Qaeda-linked insurgencies?